John Y Fang, Christopher Tolleson Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA Abstract: Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by the loss of neuronal dopamine production in the brain.Oral therapies primarily augment the dopaminergic pathway.As the disease progr
Naphthoquinones may cause oxidative stress in exposed cells and, Hay bags therefore, affect redox signaling.Here, contributions of redox cycling and alkylating properties of quinones (both natural and synthetic, such as plumbagin, juglone, lawsone, menadione, methoxy-naphthoquinones, and others) to cellular and inter-cellular signaling processes ar
Background: The global COVID-19 pandemic has prompted an urgent search for effective interventions.SARS-CoV-2 mortality/morbidity risk increases with age and for those chronic disease co-morbidities, both of which are associated with lower zinc status, as is the risk of infection.Methods: Rapid review methods will be applied to a systematic review
Superamphiphobic coatings have widespread application potential in various fields, e.g., anti-icing, anti-corrosion and self-cleaning, but are seriously limited by poor mechanical stability.Here, mechanically stable superamphiphobic coatings were fabricated by spraying the suspension composed of phase-separated silicone-modified polyester (SPET) ad